CYTOKINE MECHANISMS FOR EARLY PERIOD OF EXPERIMENTAL BACTERIAL-IMMUNE PERIODONTITIS DEVELOPMENT
نویسندگان
چکیده
منابع مشابه
Development of animal experimental periodontitis models
PURPOSE An animal periodontitis model is essential for research on the pathogenesis and treatment of periodontal disease. In this study, we have introduced a lipopolysaccharide (LPS) of a periodontal pathogen to the alveolar bone defect of experimental animals and investigated its suitability as a periodontitis model. METHODS Alveolar bone defects were made in both sides of the mandibular thi...
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When rabbits sensitized to human serum albumin (HSA) are challenged intravenously with specific antigen, fever develops and two transferable pyrogens can be demonstrated in the circulation. The first appears prior to the development of fever and has properties consistent with soluble antigen-antibody complexes. These have been shown to be pyrogenic when prepared in vitro and to produce a state ...
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BACKGROUND Bacterial invasion of host epithelial cells plays an important role in the pathogenesis of periodontitis; however, the exact mechanism of the invasion has not been investigated. METHODS Pocket epithelium biopsies in periodontitis were analysed via scanning and transmission electron microscopy using ultra-histochemical staining with ruthenium red for glycocalyx visualization. RESU...
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CD4 CD25 regulatory T (T R ) cells can inhibit a variety of autoimmune and inflammatory diseases, but the precise mechanisms by which they suppress immune responses in vivo remain unresolved. Here, we have used Helicobacter hepaticus infection of T cell–reconstituted recombination-activating gene (RAG) / mice as a model to study the ability of CD4 CD25 T R cells to inhibit bacterially triggered...
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ژورنال
عنوان ژورنال: Вісник наукових досліджень
سال: 2018
ISSN: 2415-8798,1681-276X
DOI: 10.11603/2415-8798.2018.3.9415